APLUS Simulation is an AI-powered pharmacometrics and software company specializing in AI-enabled prediction tools and quantitative solutions for drug development. We advance drug development through data-driven and mechanistic modeling approaches.
We develop AI-powered modeling tools and quantitative frameworks that support therapeutic decision-making, including systems models, AI/ML-driven simulations, and real-world applications for artificial intelligence–driven development (AIDD).
We partner with researchers, pharmaceutical and biotech companies, developers, and clinical pharmacologists to deliver high-quality scientific expertise and scalable AI-enabled solutions that accelerate human-centered, non-animal drug development.
Our team integrates AI and machine learning with mechanistic and quantitative models to enhance prediction accuracy, biomarker interpretation, and decision-making, with decades of hands-on pharmaceutical modeling experience spanning industry and academia.